Title : Nitric oxide produced endogenously is responsible for hypoxia-induced HIF-1α stabilization in colon carcinoma cells.

Pub. Date : 2012 Oct 15

PMID : 22971010






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Thiol reduction with dithiothreitol decreased HIF-1alpha stabilization in hypoxic cells, while dinitrochlorobenzene, which stabilizes S-nitrosothiols, favored its accumulation. Sulfhydryl Compounds hypoxia inducible factor 1 subunit alpha Homo sapiens