Pub. Date : 2013 Mar
PMID : 22970723
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Acute administration of ketamine in rats increases hippocampal BDNF and mTOR levels during forced swimming test. | Ketamine | mechanistic target of rapamycin kinase | Rattus norvegicus |
| 2 | Ketamine given at doses of 5, 10, and 15 mg/kg showed significant increases in relative levels of hippocampal p-mTOR (P < 0.05 for all doses) CONCLUSION: The antidepressant effect of ketamine might be related to the increased expression of BDNF and mTOR in the hippocampus of rats. | Ketamine | mechanistic target of rapamycin kinase | Rattus norvegicus |
| 3 | Ketamine given at doses of 5, 10, and 15 mg/kg showed significant increases in relative levels of hippocampal p-mTOR (P < 0.05 for all doses) CONCLUSION: The antidepressant effect of ketamine might be related to the increased expression of BDNF and mTOR in the hippocampus of rats. | Ketamine | mechanistic target of rapamycin kinase | Rattus norvegicus |
| 4 | Ketamine given at doses of 5, 10, and 15 mg/kg showed significant increases in relative levels of hippocampal p-mTOR (P < 0.05 for all doses) CONCLUSION: The antidepressant effect of ketamine might be related to the increased expression of BDNF and mTOR in the hippocampus of rats. | Ketamine | mechanistic target of rapamycin kinase | Rattus norvegicus |