Title : PI3K p110α isoform-dependent Rho GTPase Rac1 activation mediates H2S-promoted endothelial cell migration via actin cytoskeleton reorganization.

Pub. Date : 2012

PMID : 22970259






3 Functional Relationships(s)
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1 Additionally, inhibiting of extracellular signal-regulated kinase (ERK) decreased the augmented cell migration rate by H(2)S, but had no effect on Rac1 activation. Hydrogen Sulfide mitogen-activated protein kinase 1 Homo sapiens
2 Additionally, inhibiting of extracellular signal-regulated kinase (ERK) decreased the augmented cell migration rate by H(2)S, but had no effect on Rac1 activation. Hydrogen Sulfide mitogen-activated protein kinase 1 Homo sapiens
3 ERK was also shown to be involved in the action of H(2)S on endothelial cell migration, but independently of Rac1. Hydrogen Sulfide mitogen-activated protein kinase 1 Homo sapiens