Title : Evaluation of cholesterol reduction activity of methyl-β-cyclodextrin using differentiated human neurons and astrocytes.

Pub. Date : 2012 Oct

PMID : 22923786






1 Functional Relationships(s)
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1 Methyl-beta-cyclodextrin (MBCD) has been shown to reduce lysosomal cholesterol accumulation in skin fibroblasts derived from patients with Niemann Pick type C disease and in the NPC1-/- mouse model. methyl-beta-cyclodextrin NPC intracellular cholesterol transporter 1 Homo sapiens