Title : Generation and characterization of a novel multidrug resistance protein 2 humanized mouse line.

Pub. Date : 2012 Nov

PMID : 22917771






1 Functional Relationships(s)
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Protein Name
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1 We show that human MRP2 is able to compensate functionally for the loss of the mouse transporter as demonstrated by comparable bilirubin levels in the humanized mice and wild-type controls, in contrast to the hyperbilirubinemia phenotype that is observed in MRP2(-/-) mice. Bilirubin ATP binding cassette subfamily C member 2 Homo sapiens