Title : Role of M3 mAChR in in vivo and in vitro models of LPS-induced inflammatory response.

Pub. Date : 2012 Nov

PMID : 22910223






1 Functional Relationships(s)
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1 RESULTS: LPS-induced acute lung injury (ALI) was significantly improved by atropine (a non-selective mAChR antagonist) and 4-DAMP (a M3 mAChR antagonist), as indicated by the diminution of neutrophil infiltration, pulmonary vascular permeability and IL-6 and TNF-alpha production. 4-diphenylacetoxy-1,1-dimethylpiperidinium interleukin 6 Mus musculus