Title : Curcuma DMSO extracts and curcumin exhibit an anti-inflammatory and anti-catabolic effect on human intervertebral disc cells, possibly by influencing TLR2 expression and JNK activity.

Pub. Date : 2012 Aug 21

PMID : 22909087






2 Functional Relationships(s)
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1 The DMSO-soluble component curcumin, whose occurrence within the DMSO extract was verified by HPLC/MS, reduced levels of IL-1beta, IL-6, IL-8, MMP1, MMP3 and MMP13 and both caused an up-regulation of TNF-alpha. Dimethyl Sulfoxide interleukin 6 Homo sapiens
2 The DMSO-soluble component curcumin, whose occurrence within the DMSO extract was verified by HPLC/MS, reduced levels of IL-1beta, IL-6, IL-8, MMP1, MMP3 and MMP13 and both caused an up-regulation of TNF-alpha. Dimethyl Sulfoxide interleukin 6 Homo sapiens