Pub. Date : 2013 Jan
PMID : 22901690
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Docosahexaenoic acid inhibition of inflammation is partially via cross-talk between Nrf2/heme oxygenase 1 and IKK/NF-kappaB pathways. | Docosahexaenoic Acids | nuclear factor kappa B subunit 1 | Homo sapiens |
| 2 | Importantly, we show for the first time that HO-1 plays a down-regulatory role in NF-kappaB nuclear translocation, and inhibition of Nrf2 ubiquitination and proteasome activity are involved in increased cellular Nrf2 level by DHA. | Docosahexaenoic Acids | nuclear factor kappa B subunit 1 | Homo sapiens |
| 3 | In this study, we show that HO-1 plays a down-regulatory role in NF-kappaB nuclear translocation and that the protective effect of DHA against inflammation is partially via up-regulation of Nrf2-mediated HO-1 expression and inhibition of IKK/NF-kappaB signaling pathway. | Docosahexaenoic Acids | nuclear factor kappa B subunit 1 | Homo sapiens |