Pub. Date : 2012 Nov
PMID : 22899318
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | JAK inhibition with tofacitinib suppresses arthritic joint structural damage through decreased RANKL production. | tofacitinib | TNF superfamily member 11 | Homo sapiens |
| 2 | CONCLUSION: These results suggest that the JAK inhibitor tofacitinib suppresses osteoclast-mediated structural damage to arthritic joints, and this effect is secondary to decreased RANKL production. | tofacitinib | TNF superfamily member 11 | Homo sapiens |