Title : Synthesis and characterization in monkey of [11C]SP203 as a radioligand for imaging brain metabotropic glutamate 5 receptors.

Pub. Date : 2012 Dec

PMID : 22885775






1 Functional Relationships(s)
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1 PURPOSE: [(18)F]SP203 (3-fluoro-5-(2-(2-([(18)F]fluoromethyl)-thiazol-4-yl)ethynyl)benzonitrile) is an effective high-affinity and selective radioligand for imaging metabotropic 5 receptors (mGluR5) in human brain with PET. Fluorine-18 glutamate receptor, ionotropic, kainate 1 Mus musculus