Title : Single-channel electrophysiology reveals a distinct and uniform pore complex formed by α-synuclein oligomers in lipid membranes.

Pub. Date : 2012

PMID : 22880029






2 Functional Relationships(s)
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1 In this study, employing a setup for single-channel electrophysiology, we found that addition of iron-induced alpha-synuclein oligomers resulted in quantized and stepwise increases in bilayer conductance indicating insertion of distinct transmembrane pores. Iron synuclein alpha Homo sapiens
2 Our findings indicate that iron-induced alpha-synuclein oligomers can form a uniform and distinct pore species with characteristic electrophysiological properties. Iron synuclein alpha Homo sapiens