Title : Quiescent fibroblasts are protected from proteasome inhibition-mediated toxicity.

Pub. Date : 2012 Sep

PMID : 22875985






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Moreover, MG132 treatment of proliferating fibroblasts led to increased superoxide anion levels, juxtanuclear accumulation of ubiquitin- and p62/SQSTM1-positive protein aggregates, and apoptotic cell death, whereas MG132-treated quiescent cells displayed fewer juxtanuclear protein aggregates, less apoptosis, and higher levels of mitochondrial superoxide dismutase. benzyloxycarbonylleucyl-leucyl-leucine aldehyde sequestosome 1 Homo sapiens
2 Moreover, MG132 treatment of proliferating fibroblasts led to increased superoxide anion levels, juxtanuclear accumulation of ubiquitin- and p62/SQSTM1-positive protein aggregates, and apoptotic cell death, whereas MG132-treated quiescent cells displayed fewer juxtanuclear protein aggregates, less apoptosis, and higher levels of mitochondrial superoxide dismutase. benzyloxycarbonylleucyl-leucyl-leucine aldehyde sequestosome 1 Homo sapiens