Title : Human mesenchymal stem/stromal cells cultured as spheroids are self-activated to produce prostaglandin E2 that directs stimulated macrophages into an anti-inflammatory phenotype.

Pub. Date : 2012 Oct

PMID : 22865689






1 Functional Relationships(s)
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1 Moreover, production of PGE2 by hMSC spheroids was dependent on the activity of caspases and NFkappaB activation in the hMSCs. Dinoprostone nuclear factor kappa B subunit 1 Homo sapiens