Pub. Date : 2011 Dec 21
PMID : 22860163
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | "Clicked" sugar-curcumin conjugate: modulator of amyloid-beta and tau peptide aggregation at ultralow concentrations. | Curcumin | microtubule associated protein tau | Homo sapiens |
2 | The synthesis of a water/plasma soluble, noncytotoxic, "clicked" sugar-derivative of curcumin with amplified bioefficacy in modulating amyloid-beta and tau peptide aggregation is presented. | Curcumin | microtubule associated protein tau | Homo sapiens |
3 | Curcumin inhibits amyloid-beta and tau peptide aggregation at micromolar concentrations; the sugar-curcumin conjugate inhibits Abeta and tau peptide aggregation at concentrations as low as 8 nM and 0.1 nM, respectively. | Curcumin | microtubule associated protein tau | Homo sapiens |
4 | Curcumin inhibits amyloid-beta and tau peptide aggregation at micromolar concentrations; the sugar-curcumin conjugate inhibits Abeta and tau peptide aggregation at concentrations as low as 8 nM and 0.1 nM, respectively. | Curcumin | microtubule associated protein tau | Homo sapiens |