Title : BDNF may play a differential role in the protective effect of the mGluR2/3 agonist LY379268 on striatal projection neurons in R6/2 Huntington's disease mice.

Pub. Date : 2012 Sep 14

PMID : 22820300






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 BDNF may play a differential role in the protective effect of the mGluR2/3 agonist LY379268 on striatal projection neurons in R6/2 Huntington"s disease mice. LY 379268 glutamate receptor, metabotropic 2 Mus musculus
2 We have found that daily subcutaneous injection with a maximum tolerated dose (MTD) of the mGluR2/3 agonist LY379268 (20mg/kg) beginning at 4 weeks dramatically improves the phenotype in R6/2 mice. LY 379268 glutamate receptor, metabotropic 2 Mus musculus