Pub. Date : 2013 Mar
PMID : 22818713
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Moreover, silibinin repressed the phenylephrine-induced phosphorylation of ERK1/2 kinases, while it appeared to inhibit the weakly activated by phenylephrine phosphorylation of Akt. | Phenylephrine | AKT serine/threonine kinase 1 | Rattus norvegicus |
| 2 | Based on our results, silibinin may attenuate the phenylephrine-induced hypertrophic response of H9c2 cells via antioxidant mechanisms involving mainly the inhibition of the intracellular signaling pathways mediated by ERK1/2 MAPKs and Akt. | Phenylephrine | AKT serine/threonine kinase 1 | Rattus norvegicus |