Title : Repeated dose toxicity and relative potency of 1,2,3,4,6,7-hexachloronaphthalene (PCN 66) 1,2,3,5,6,7-hexachloronaphthalene (PCN 67) compared to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) for induction of CYP1A1, CYP1A2 and thymic atrophy in female Harlan Sprague-Dawley rats.

Pub. Date : 2012 Nov 15

PMID : 22813907






2 Functional Relationships(s)
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Protein Name
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1 Significant increases in CYP1A1 and CYP1A2 associated enzyme activity were observed in all animals exposed to TCDD, PCN 66 and PCN 67. Pregnenolone Carbonitrile cytochrome P450, family 1, subfamily a, polypeptide 1 Rattus norvegicus
2 Significant increases in CYP1A1 and CYP1A2 associated enzyme activity were observed in all animals exposed to TCDD, PCN 66 and PCN 67. Pregnenolone Carbonitrile cytochrome P450, family 1, subfamily a, polypeptide 1 Rattus norvegicus