Pub. Date : 2012 Jul 17
PMID : 22810896
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Unlike other TLRs, TLR3 requires phosphorylation of two specific tyrosine residues in its cytoplasmic domain to recruit the adaptor protein TRIF (Toll-interleukin-1 receptor domain-containing adaptor protein inducing interferon-beta) and initiate the antiviral response. | Tyrosine | toll like receptor 3 | Homo sapiens |
| 2 | We showed that two protein tyrosine kinases, the epidermal growth factor receptor (EGFR) ErbB1 and Src, bound sequentially to dsRNA-activated TLR3 and phosphorylated the two tyrosine residues. | Tyrosine | toll like receptor 3 | Homo sapiens |