PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22810896-4 2012 Unlike other TLRs, TLR3 requires phosphorylation of two specific tyrosine residues in its cytoplasmic domain to recruit the adaptor protein TRIF (Toll-interleukin-1 receptor domain-containing adaptor protein inducing interferon-beta) and initiate the antiviral response. Tyrosine 65-73 toll like receptor 3 Homo sapiens 19-23 22810896-5 2012 We showed that two protein tyrosine kinases, the epidermal growth factor receptor (EGFR) ErbB1 and Src, bound sequentially to dsRNA-activated TLR3 and phosphorylated the two tyrosine residues. Tyrosine 27-35 toll like receptor 3 Homo sapiens 142-146