Pub. Date : 2012 Dec
PMID : 22804629
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We have found that modification of this Cys111 with 2-ME (2-mercaptoethanol; 2-ME-SOD1) stabilizes the protein and the mechanism may provide insights into destabilization and the formation of aggregated proteins. | Mercaptoethanol | superoxide dismutase 1 | Homo sapiens |
2 | We have found that modification of this Cys111 with 2-ME (2-mercaptoethanol; 2-ME-SOD1) stabilizes the protein and the mechanism may provide insights into destabilization and the formation of aggregated proteins. | Mercaptoethanol | superoxide dismutase 1 | Homo sapiens |
3 | We have found that modification of this Cys111 with 2-ME (2-mercaptoethanol; 2-ME-SOD1) stabilizes the protein and the mechanism may provide insights into destabilization and the formation of aggregated proteins. | Mercaptoethanol | superoxide dismutase 1 | Homo sapiens |
4 | Here, we determined the crystal structure of 2-ME-SOD1 and find that the 2-ME moieties in both subunits interact asymmetrically at the dimer interface and that there is an asymmetric configuration of segment Gly108 to Cys111 in loop VI. | Mercaptoethanol | superoxide dismutase 1 | Homo sapiens |