Title : T-2 toxin enhances catabolic activity of hypertrophic chondrocytes through ROS-NF-κB-HIF-2α pathway.

Pub. Date : 2012 Oct

PMID : 22800716






1 Functional Relationships(s)
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Protein Name
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1 Bay11-7085 (an inhibitor of NF-kappaB pathway) inhibited the up-regulation of HIF-2alpha, and N-acetyl-l-cysteine (a ROS scavenger) inhibited both the decrease of IkappaB-alpha and the up-regulation of HIF-2alpha. BAY 11-7085 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus