Title : PPARδ Activation Rescues Pancreatic β-Cell Line INS-1E from Palmitate-Induced Endoplasmic Reticulum Stress through Enhanced Fatty Acid Oxidation.

Pub. Date : 2012

PMID : 22792088






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1 PPARdelta Activation Rescues Pancreatic beta-Cell Line INS-1E from Palmitate-Induced Endoplasmic Reticulum Stress through Enhanced Fatty Acid Oxidation. Fatty Acids peroxisome proliferator activated receptor delta Homo sapiens
2 However, the correlation between PPARdelta of fatty acids and ER stress of pancreatic beta cells is not quite clear till date. Fatty Acids peroxisome proliferator activated receptor delta Homo sapiens
3 Further, we illustrate that PPARdelta attenuates palmitate-induced ER stress by promoting fatty acid oxidation through treatment with etomoxir, an inhibitor of fatty acid oxidation. Fatty Acids peroxisome proliferator activated receptor delta Homo sapiens
4 Further, we illustrate that PPARdelta attenuates palmitate-induced ER stress by promoting fatty acid oxidation through treatment with etomoxir, an inhibitor of fatty acid oxidation. Fatty Acids peroxisome proliferator activated receptor delta Homo sapiens
5 Our work elucidates the protective effect of PPARdelta on the fatty-acid-induced toxicity of pancreatic beta cells. Fatty Acids peroxisome proliferator activated receptor delta Homo sapiens