Title : Designing allosteric regulators of thrombin. Monosulfated benzofuran dimers selectively interact with Arg173 of exosite 2 to induce inhibition.

Pub. Date : 2012 Aug 9

PMID : 22788964






1 Functional Relationships(s)
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1 Earlier, we reported on the design of sulfated benzofuran dimers (SBDs) as allosteric inhibitors of thrombin (Sidhu et al. benzofuran coagulation factor II, thrombin Homo sapiens