Title : Angiotensin II induces vascular endocannabinoid release, which attenuates its vasoconstrictor effect via CB1 cannabinoid receptors.

Pub. Date : 2012 Sep 7

PMID : 22787147






1 Functional Relationships(s)
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1 Inverse agonists of CB(1)R (SR141716 and AM251) and inhibition of diacylglycerol lipase using tetrahydrolipstatin also augmented the Ang II-induced vasoconstriction, suggesting that endocannabinoid release modulates this process via CB(1)R activation. Orlistat angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Mus musculus