Title : Suppression of NF-κB signaling by andrographolide with a novel mechanism in human platelets: regulatory roles of the p38 MAPK-hydroxyl radical-ERK2 cascade.

Pub. Date : 2012 Oct 1

PMID : 22771630






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 SB203580, NAC (a free-radical scavenger), and BAY11-7082 (an inhibitor of NF-kappaB) all diminished ERK2 phosphorylation, whereas PD98059, BAY11-7082, and NAC had no effects on p38 MAPK phosphorylation. 3-(4-methylphenylsulfonyl)-2-propenenitrile mitogen-activated protein kinase 1 Homo sapiens
2 SB203580, NAC (a free-radical scavenger), and BAY11-7082 (an inhibitor of NF-kappaB) all diminished ERK2 phosphorylation, whereas PD98059, BAY11-7082, and NAC had no effects on p38 MAPK phosphorylation. 3-(4-methylphenylsulfonyl)-2-propenenitrile mitogen-activated protein kinase 1 Homo sapiens
3 SB203580, NAC (a free-radical scavenger), and BAY11-7082 (an inhibitor of NF-kappaB) all diminished ERK2 phosphorylation, whereas PD98059, BAY11-7082, and NAC had no effects on p38 MAPK phosphorylation. 3-(4-methylphenylsulfonyl)-2-propenenitrile mitogen-activated protein kinase 1 Homo sapiens