Title : Intradermal Spitz nevus differentiated from reticulohistiocytic granuloma by immunoreactivity to S-100 protein.

Pub. Date : 1990 Sep

PMID : 2277146






1 Functional Relationships(s)
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1 Although a few melanosomes in the tumor cells seen in electron microscopic examination provided crucial proof for the diagnosis of Spitz nevus, the positive reactivity to S-100 protein in ordinary formalin-fixed, paraffin-embedded tissues proved to be very useful in the differentiation of Spitz nevus from tumors of histiocytic origin, especially those of the mononuclear phagocytic system. Formaldehyde S100 calcium binding protein A1 Homo sapiens