Protein Name | S100 calcium binding protein A1 |
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Organism | Homo sapiens |
Gene ID | 6271 |
Gene Symbol | S100A1 |
UniProt | P23297 (S10A1_HUMAN), A0A0S2Z4H2 (A0A0S2Z4H2_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
218
Total Number of Articles : 341 |
Description |
S100 calcium binding protein A1 |
Gene Summary |
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. [provided by RefSeq, Jul 2008] |
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