Protein Name S100 calcium binding protein A1
Organism Homo sapiens
Gene ID 6271
Gene Symbol

S100A1

UniProt P23297 (S10A1_HUMAN), A0A0S2Z4H2 (A0A0S2Z4H2_HUMAN)
Relationships Total Number of functionally related compound(s) : 218
Total Number of Articles : 341
Description

S100 calcium binding protein A1

Gene Summary

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. [provided by RefSeq, Jul 2008]

synonyms
  • protein S100-A1
  • S-100 protein alpha chain
  • S-100 protein subunit alpha
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Properties