Title : Block of human CaV3 channels by the diuretic amiloride.

Pub. Date : 2012 Oct

PMID : 22767612






1 Functional Relationships(s)
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1 By performing whole-cell patch-clamp recordings of human embryonic kidney 293 cells stably expressing human Ca(V)3 channels, we found that amiloride blocked the human Ca(V)3 channels in a concentration-response manner; the IC50 for Ca(V)3.2 channels (62 muM) was 13-fold lower than that for Ca(V)3.1 and Ca(V)3.3. Amiloride latexin Homo sapiens