Title : Gambogic acid as a non-competitive inhibitor of ATP-binding cassette transporter B1 reverses the multidrug resistance of human epithelial cancers by promoting ATP-binding cassette transporter B1 protein degradation.

Pub. Date : 2013 Jan

PMID : 22759348






1 Functional Relationships(s)
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1 It was also found that GA coordinated with other anti-cancer drugs (such as adriamycin, docetaxel, verapamil and protopanaxadiol) to enhance cellular cytotoxicity on human epithelial cancer cell lines with higher ABCB1 expression levels. protopanaxadiol ATP binding cassette subfamily B member 1 Homo sapiens