Title : Effect of age and gender on the relationship between alcohol consumption and serum GGT: time to recalibrate goals for normal ranges.

Pub. Date : 2012 Sep-Oct

PMID : 22753786






5 Functional Relationships(s)
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1 Therefore, further information on the associations between ethanol intake and GGT activities in apparently healthy individuals appears warranted. Ethanol gamma-glutamyltransferase light chain family member 3 Homo sapiens
2 RESULTS: In men over 40 years, a reported regular consumption of 8 standard ethanol doses ("dose" = 12 g ethanol) or more per week was found to lead to a significant elevation in serum GGT activities, whereas those below 40 showed first significant changes not until the reported ethanol intake exceeded 14 doses per week. Ethanol gamma-glutamyltransferase light chain family member 3 Homo sapiens
3 RESULTS: In men over 40 years, a reported regular consumption of 8 standard ethanol doses ("dose" = 12 g ethanol) or more per week was found to lead to a significant elevation in serum GGT activities, whereas those below 40 showed first significant changes not until the reported ethanol intake exceeded 14 doses per week. Ethanol gamma-glutamyltransferase light chain family member 3 Homo sapiens
4 RESULTS: In men over 40 years, a reported regular consumption of 8 standard ethanol doses ("dose" = 12 g ethanol) or more per week was found to lead to a significant elevation in serum GGT activities, whereas those below 40 showed first significant changes not until the reported ethanol intake exceeded 14 doses per week. Ethanol gamma-glutamyltransferase light chain family member 3 Homo sapiens
5 CONCLUSION: The data pertaining to the present population sample indicate that rather low levels of reported regular ethanol consumption lead to elevated levels of GGT and that age over 40 markedly enhances the impact of alcohol consumption on GGT activity. Ethanol gamma-glutamyltransferase light chain family member 3 Homo sapiens