| Protein Name | gamma-glutamyltransferase light chain family member 3 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 728226 |
| Gene Symbol | GGTLC3 |
| UniProt | - |
| Relationships |
Total Number of functionally related compound(s) :
138
Total Number of Articles : 251 |
Description |
gamma-glutamyltransferase light chain family member 3 |
| Gene Summary |
Gamma-glutamyltransferase-1 (GGT1; MIM 612346) is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. Autocatalytic cleavage of the GGT1 precursor polypeptide produces a heavy chain and a light chain that associate with each other to form the functional enzyme. Light chain-only GGTs, such as GGTLC3, contain a region corresponding to the GGT1 light chain, but they lack the membrane-anchoring heavy chain region (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM, Oct 2008] |
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| Properties | |