Title : Delta-tocotrienol augments cisplatin-induced suppression of non-small cell lung cancer cells via inhibition of the Notch-1 pathway.

Pub. Date : 2012 Jul

PMID : 22753722






1 Functional Relationships(s)
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1 These results suggest that down-regulation of Notch-1, via inhibition of NF-kappaB signaling pathways by delta-tocotrienol and cisplatin, in combination, could provide a potential novel approach for tumor arrest in NSCLC, while lowering the effective dose of cisplatin. Cisplatin nuclear factor kappa B subunit 1 Homo sapiens