Title : CHOP down-regulates cFLIP(L) expression by promoting ubiquitin/proteasome-mediated cFLIP(L) degradation.

Pub. Date : 2012 Dec

PMID : 22753273






2 Functional Relationships(s)
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1 We found that treatment of Caki cells with CHOP-inducing drugs including withaferin A, thapsigargin, brefeldin A, and silybin led to a strong reduction in cFLIP(L) protein levels together with a concomitant increase in the CHOP protein. Thapsigargin DNA damage inducible transcript 3 Homo sapiens
2 We found that treatment of Caki cells with CHOP-inducing drugs including withaferin A, thapsigargin, brefeldin A, and silybin led to a strong reduction in cFLIP(L) protein levels together with a concomitant increase in the CHOP protein. Thapsigargin DNA damage inducible transcript 3 Homo sapiens