Pub. Date : 2012 Feb
PMID : 22740939
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Chemically modified heparins inhibit fibrinogen-bridged indirect adhesion between tumor cells and platelets. | Heparin | fibrinogen beta chain | Homo sapiens |
| 2 | In the present study, we aimed to detect the effects of 8 chemically modified heparins on the binding of fibrinogen to platelets or tumor cells using flow cytometry assays, as well as the fibrinogen-bridged adhesion of platelets and tumor cells using flow chamber assays. | Heparin | fibrinogen beta chain | Homo sapiens |
| 3 | These data indicate that chemically modified heparins should be potential inhibitors for the fibrinogen-bridged indirect adhesion of platelets and tumor cells, which provides a novel explanation of the anti-adhesion property of heparin and proposes a new anti-metastatic target for cancer treatment. | Heparin | fibrinogen beta chain | Homo sapiens |
| 4 | These data indicate that chemically modified heparins should be potential inhibitors for the fibrinogen-bridged indirect adhesion of platelets and tumor cells, which provides a novel explanation of the anti-adhesion property of heparin and proposes a new anti-metastatic target for cancer treatment. | Heparin | fibrinogen beta chain | Homo sapiens |