Title : MLH1-deficient HCT116 colon tumor cells exhibit resistance to the cytostatic and cytotoxic effect of the poly(A) polymerase inhibitor cordycepin (3'-deoxyadenosine) in vitro.

Pub. Date : 2012 Feb

PMID : 22740928






1 Functional Relationships(s)
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1 MLH1-deficient cells also exhibited reduced susceptibility to apoptosis upon treatment with cordycepin, as demonstrated by the reduced PARP-1 cleavage. cordycepin poly(ADP-ribose) polymerase 1 Homo sapiens