Pub. Date : 2012 Jan
PMID : 22740861
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Sequential irinotecan hydrochloride/S-1 for S-1-resistant inoperable gastric cancer: A feasibility study. | Irinotecan | proteasome 26S subunit, non-ATPase 1 | Homo sapiens |
| 2 | Irinotecan hydrochloride (CPT-11) is reported to be involved in the downregulation of thymidylate synthase (TS), a target molecule of 5-fluorouracil (5-FU) and oral fluoropyrimidine S-1. | Irinotecan | proteasome 26S subunit, non-ATPase 1 | Homo sapiens |
| 3 | Irinotecan hydrochloride (CPT-11) is reported to be involved in the downregulation of thymidylate synthase (TS), a target molecule of 5-fluorouracil (5-FU) and oral fluoropyrimidine S-1. | Irinotecan | proteasome 26S subunit, non-ATPase 1 | Homo sapiens |
| 4 | Therefore, we hypothesized that a preceding administration of CPT-11 against S-1-resistant tumors may recover sensitivity to S-1. | Irinotecan | proteasome 26S subunit, non-ATPase 1 | Homo sapiens |
| 5 | Therefore, we hypothesized that a preceding administration of CPT-11 against S-1-resistant tumors may recover sensitivity to S-1. | Irinotecan | proteasome 26S subunit, non-ATPase 1 | Homo sapiens |