Pub. Date : 2012 Jan
PMID : 22730687
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: The frequency (19.1%) of XRCC1-194 Trp/Trp in case group was significantly higher than that (10.9%) in control group (P < 0.05), OR for lung cancer was 2.215 (95% CI: 1.276-3.845). | Tryptophan | X-ray repair cross complementing 1 | Homo sapiens |
| 2 | RESULTS: The frequency (19.1%) of XRCC1-194 Trp/Trp in case group was significantly higher than that (10.9%) in control group (P < 0.05), OR for lung cancer was 2.215 (95% CI: 1.276-3.845). | Tryptophan | X-ray repair cross complementing 1 | Homo sapiens |
| 3 | Interaction analysis of gene polymorphisms and environment factors indicated that there was interactions between XRCC1-194 Trp/Trp and XRCC1-280 His/His genotypes and smoking. | Tryptophan | X-ray repair cross complementing 1 | Homo sapiens |
| 4 | Interaction analysis of gene polymorphisms and environment factors indicated that there was interactions between XRCC1-194 Trp/Trp and XRCC1-280 His/His genotypes and smoking. | Tryptophan | X-ray repair cross complementing 1 | Homo sapiens |
| 5 | The risks of lung cancer in smokers with XRCC1-194 Arg/Trp+Trp/Trp and XRCC1-280 His/His+Arg/His were 4.889 (95% CI: 2.828-8.452) and 6.281(95% CI: 3.572-11.046), respectively. | Tryptophan | X-ray repair cross complementing 1 | Homo sapiens |
| 6 | CONCLUSION: These findings supported the hypothesis that the interaction of polymorphisms of XRCC1-194 Trp/Trp, XRCC1-280 His/His with smoking resulted in the increased risk of lung cancer, and the polymorphisms of XRCC and smoking could play an role in development of lung cancer. | Tryptophan | X-ray repair cross complementing 1 | Homo sapiens |
| 7 | CONCLUSION: These findings supported the hypothesis that the interaction of polymorphisms of XRCC1-194 Trp/Trp, XRCC1-280 His/His with smoking resulted in the increased risk of lung cancer, and the polymorphisms of XRCC and smoking could play an role in development of lung cancer. | Tryptophan | X-ray repair cross complementing 1 | Homo sapiens |