Title : Correlation between mammalian cell cytotoxicity of flavonoids and the redox potential of phenoxyl radical/phenol couple.

Pub. Date : 2012

PMID : 22696302






1 Functional Relationships(s)
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1 It shows that although the prooxidant action of flavonoids may be the main factor in their cytotoxicity, the hydroxylation and oxidative demethylation by cytochromes P-450 and O-methylation by catechol-O-methyltransferase can significantly modulate the cytotoxicity of the parent compounds. Flavonoids catechol-O-methyltransferase Homo sapiens