Title : CDK inhibitors upregulate BH3-only proteins to sensitize human myeloma cells to BH3 mimetic therapies.

Pub. Date : 2012 Aug 15

PMID : 22693249






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Mechanistic investigations revealed that flavopiridol inhibited Mcl-1 transcription but increased transcription of Bim and its binding to Bcl-2/Bcl-xL. alvocidib MCL1 apoptosis regulator, BCL2 family member Homo sapiens