Title : A targeted enzyme approach to sensitization of tyrosine kinase inhibitor-resistant breast cancer cells.

Pub. Date : 2012 Oct 1

PMID : 22687878






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 We show that reactive oxygen species (ROS), known to damage cellular macromolecules and to modulate signaling cascades in a variety of human diseases including cancers, appear to play a critical role in mediating EGFR TKI-resistance. Reactive Oxygen Species epidermal growth factor receptor Homo sapiens
2 We show that reactive oxygen species (ROS), known to damage cellular macromolecules and to modulate signaling cascades in a variety of human diseases including cancers, appear to play a critical role in mediating EGFR TKI-resistance. Reactive Oxygen Species epidermal growth factor receptor Homo sapiens