Pub. Date : 2012 Jul
PMID : 22673740
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Sorafenib and pemetrexed toxicity in cancer cells is mediated via SRC-ERK signaling. | Pemetrexed | mitogen-activated protein kinase 3 | Homo sapiens |
| 2 | Collectively these findings demonstrate that ERK1/2 plays an essential role downstream of SRC in pemetrexed and sorafenib lethality and that PP2A plays an important role in regulating this process. | Pemetrexed | mitogen-activated protein kinase 3 | Homo sapiens |