Title : Wogonin potentiates cisplatin-induced cancer cell apoptosis through accumulation of intracellular reactive oxygen species.

Pub. Date : 2012 Aug

PMID : 22665077






1 Functional Relationships(s)
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1 It was found for the first time that wogonin is able to sensitize cisplatin-induced apoptosis in both A549 cells and HeLa cells as indicated by the potentiation of activation of caspase-3, and cleavage of the caspase-3 substrate PARP in wogonin and cisplatin co-treated cells. Cisplatin collagen type XI alpha 2 chain Homo sapiens