Pub. Date : 2012 Aug 1
PMID : 22659397
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tianeptine treatment induces antidepressive-like effects and alters BDNF and energy metabolism in the brain of rats. | tianeptine | brain-derived neurotrophic factor | Rattus norvegicus |
| 2 | The BDNF levels were increased in the prefrontal cortex with tianeptine and decreased in the nucleus accumbens after acute treatment; in chronic treatment, BDNF levels were increased in the prefrontal and hippocampus with tianeptine. | tianeptine | brain-derived neurotrophic factor | Rattus norvegicus |
| 3 | The BDNF levels were increased in the prefrontal cortex with tianeptine and decreased in the nucleus accumbens after acute treatment; in chronic treatment, BDNF levels were increased in the prefrontal and hippocampus with tianeptine. | tianeptine | brain-derived neurotrophic factor | Rattus norvegicus |
| 4 | The BDNF levels were increased in the prefrontal cortex with tianeptine and decreased in the nucleus accumbens after acute treatment; in chronic treatment, BDNF levels were increased in the prefrontal and hippocampus with tianeptine. | tianeptine | brain-derived neurotrophic factor | Rattus norvegicus |
| 5 | In conclusion, tianeptine exerted antidepressant-like behavior which can be attributed to its effects on pathways related to depression, such as BDNF and metabolism energy. | tianeptine | brain-derived neurotrophic factor | Rattus norvegicus |