Title : Toll-like receptor 4 ligation confers chemoresistance to docetaxel on PC-3 human prostate cancer cells.

Pub. Date : 2012 Aug

PMID : 22648782






1 Functional Relationships(s)
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1 Downregulation of TLR4 using small-interference RNA sensitized PC-3 cells to docetaxel-induced apoptosis as determined by annexin V staining and poly (ADP-ribose) polymerase cleavage, which was coupled with increased Bax expression and decreased Bcl-2. Docetaxel annexin A5 Homo sapiens