Pub. Date : 2012 Aug
PMID : 22634399
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We have recently reported that divalent metal transporter 1 (DMT1) is upregulated in an AD transgenic mouse brain, and that silencing of DMT1, which reduces cellular iron influx, results in inhibition of amyloidogenesis in vitro, suggesting a potential target of DMT1 for AD therapy. | Iron | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 | Mus musculus |
2 | We have recently reported that divalent metal transporter 1 (DMT1) is upregulated in an AD transgenic mouse brain, and that silencing of DMT1, which reduces cellular iron influx, results in inhibition of amyloidogenesis in vitro, suggesting a potential target of DMT1 for AD therapy. | Iron | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 | Mus musculus |
3 | We have recently reported that divalent metal transporter 1 (DMT1) is upregulated in an AD transgenic mouse brain, and that silencing of DMT1, which reduces cellular iron influx, results in inhibition of amyloidogenesis in vitro, suggesting a potential target of DMT1 for AD therapy. | Iron | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 | Mus musculus |
4 | We have recently reported that divalent metal transporter 1 (DMT1) is upregulated in an AD transgenic mouse brain, and that silencing of DMT1, which reduces cellular iron influx, results in inhibition of amyloidogenesis in vitro, suggesting a potential target of DMT1 for AD therapy. | Iron | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 | Mus musculus |