Title : Statins increase cytochrome P450 4F3-mediated eicosanoids production in human liver cells: a PXR dependent mechanism.

Pub. Date : 2012 Aug 15

PMID : 22634049






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Statins induced CYP4F3B mRNA, protein and the production of 20-hydroxyeicosatetraenoic acid (20-HETE), a product of arachidonic acid metabolism and a peroxisome proliferator activated receptor (PPAR) ligand. 20-hydroxy-5,8,11,14-eicosatetraenoic acid peroxisome proliferator activated receptor alpha Homo sapiens
2 Statins induced CYP4F3B mRNA, protein and the production of 20-hydroxyeicosatetraenoic acid (20-HETE), a product of arachidonic acid metabolism and a peroxisome proliferator activated receptor (PPAR) ligand. 20-hydroxy-5,8,11,14-eicosatetraenoic acid peroxisome proliferator activated receptor alpha Homo sapiens
3 Statins induced CYP4F3B mRNA, protein and the production of 20-hydroxyeicosatetraenoic acid (20-HETE), a product of arachidonic acid metabolism and a peroxisome proliferator activated receptor (PPAR) ligand. 20-hydroxy-5,8,11,14-eicosatetraenoic acid peroxisome proliferator activated receptor alpha Homo sapiens
4 Statins induced CYP4F3B mRNA, protein and the production of 20-hydroxyeicosatetraenoic acid (20-HETE), a product of arachidonic acid metabolism and a peroxisome proliferator activated receptor (PPAR) ligand. 20-hydroxy-5,8,11,14-eicosatetraenoic acid peroxisome proliferator activated receptor alpha Homo sapiens