Title : β1 -adrenergic receptor autoantibodies from heart failure patients enhanced TNF-α secretion in RAW264.7 macrophages in a largely PKA-dependent fashion.

Pub. Date : 2012 Oct

PMID : 22628174






2 Functional Relationships(s)
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1 Autoantibodies against the second extracellular loop of beta(1) -adrenergic receptor (beta(1) -AA) not only contribute to increased susceptibility to heart failure, but also play a causative role in myocardial remodeling through their catecholamine-like effects via binding with the beta(1) -adrenergic receptor. Catecholamines adrenoceptor beta 1 Homo sapiens
2 Autoantibodies against the second extracellular loop of beta(1) -adrenergic receptor (beta(1) -AA) not only contribute to increased susceptibility to heart failure, but also play a causative role in myocardial remodeling through their catecholamine-like effects via binding with the beta(1) -adrenergic receptor. Catecholamines adrenoceptor beta 1 Homo sapiens