Protein Name adrenoceptor beta 1
Organism Homo sapiens
Gene ID 153
Gene Symbol

ADRB1

UniProt P08588 (ADRB1_HUMAN)
Relationships Total Number of functionally related compound(s) : 352
Total Number of Articles : 841
Description

adrenoceptor beta 1

Gene Summary

The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Beta-1 adrenoceptors are predominately located in the heart. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq, Sep 2019]

synonyms
  • beta-1 adrenergic receptor
  • adrenergic, beta-1-, receptor
  • beta-1 adrenoceptor
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Properties