Title : Population pharmacokinetics and pharmacogenetics of everolimus in renal transplant patients.

Pub. Date : 2012 Jul 1

PMID : 22624503






1 Functional Relationships(s)
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1 The primary objective of this study was to improve prediction of everolimus systemic exposure in renal transplant patients by describing the pharmacokinetics of everolimus and identifying the influence of demographic factors and a selection of polymorphisms in genes coding for ABCB1, CYP3A5, CYP2C8 and PXR. Everolimus cytochrome P450 family 2 subfamily C member 8 Homo sapiens