Title : Pharmacokinetic interaction between the hepatitis C virus protease inhibitor boceprevir and cyclosporine and tacrolimus in healthy volunteers.

Pub. Date : 2012 Nov

PMID : 22576324






1 Functional Relationships(s)
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1 Cyclosporine and tacrolimus are calcineurin inhibitor immunosuppressants used to prevent organ rejection after liver transplantation; both are substrates of CYP3A4. Tacrolimus cytochrome P450 family 3 subfamily A member 4 Homo sapiens